Búsqueda | Portal de Búsqueda de la BVS España

1.

Pharmacological targeting of netrin-1 inhibits EMT in cancer.

Lengrand, Justine; Pastushenko, Ievgenia; Vanuytven, Sebastiaan; Song, Yura; Venet, David; Sarate, Rahul M; Bellina, Melanie; Moers, Virginie; Boinet, Alice; Sifrim, Alejandro; Rama, Nicolas; Ducarouge, Benjamin; Van Herck, Jens; Dubois, Christine; Scozzaro, Samuel; Lemaire, Sophie; Gieskes, Sarah; Bonni, Sophie; Collin, Amandine; Braissand, Nicolas; Allard, Justine; Zindy, Egor; Decaestecker, Christine; Sotiriou, Christos; Salmon, Isabelle; Mehlen, Patrick; Voet, Thierry; Bernet, Agnès; Blanpain, Cédric.

Nature; 620(7973): 402-408, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37532929

2.

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.

Cassier, Philippe A; Navaridas, Raul; Bellina, Melanie; Rama, Nicolas; Ducarouge, Benjamin; Hernandez-Vargas, Hector; Delord, Jean-Pierre; Lengrand, Justine; Paradisi, Andrea; Fattet, Laurent; Garin, Gwenaële; Gheit, Hanane; Dalban, Cecile; Pastushenko, Ievgenia; Neves, David; Jelin, Remy; Gadot, Nicolas; Braissand, Nicolas; Léon, Sophie; Degletagne, Cyril; Matias-Guiu, Xavier; Devouassoux-Shisheboran, Mojgan; Mery-Lamarche, Eliane; Allard, Justine; Zindy, Egor; Decaestecker, Christine; Salmon, Isabelle; Perol, David; Dolcet, Xavi; Ray-Coquard, Isabelle; Blanpain, Cédric; Bernet, Agnès; Mehlen, Patrick.

Nature; 620(7973): 409-416, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37532934

3.

The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor.

Wang, Hong; Boussouar, Amina; Mazelin, Laetitia; Tauszig-Delamasure, Servane; Sun, Yan; Goldschneider, David; Paradisi, Andrea; Mehlen, Patrick.

Mol Cell; 72(3): 413-425.e5, 2018 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-30293784

4.

Netrin-1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson's disease features.

Jasmin, Mélissa; Ahn, Eun Hee; Voutilainen, Merja H; Fombonne, Joanna; Guix, Catherine; Viljakainen, Tuulikki; Kang, Seong Su; Yu, Li-Ying; Saarma, Mart; Mehlen, Patrick; Ye, Keqiang.

EMBO J; 40(3): e105537, 2021 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-33351190

5.

Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human.

Diaz-delCastillo, Marta; Palasca, Oana; Nemler, Tim T; Thygesen, Didde M; Chávez-Saldaña, Norma A; Vázquez-Mora, Juan A; Ponce Gomez, Lizeth Y; Jensen, Lars Juhl; Evans, Holly; Andrews, Rebecca E; Mandal, Aritri; Neves, David; Mehlen, Patrick; Caruso, James P; Dougherty, Patrick M; Price, Theodore J; Chantry, Andrew; Lawson, Michelle A; Andersen, Thomas L; Jimenez-Andrade, Juan M; Heegaard, Anne-Marie.

J Neurosci; 43(29): 5414-5430, 2023 07 19.

Artículo en Inglés | MEDLINE | ID: mdl-37286351

6.

Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity.

Sun, Yan; Manceau, Ambroise; Frydman, Lisa; Cappuccio, Lucie; Neves, David; Basso, Valeria; Wang, Hong; Fombonne, Joanna; Maisse, Carine; Mehlen, Patrick; Paradisi, Andrea.

Proc Natl Acad Sci U S A; 118(36)2021 09 07.

Artículo en Inglés | MEDLINE | ID: mdl-34470826

7.

Hepatic inflammation elicits production of proinflammatory netrin-1 through exclusive activation of translation.

Barnault, Romain; Verzeroli, Claire; Fournier, Carole; Michelet, Maud; Redavid, Anna Rita; Chicherova, Ievgeniia; Plissonnier, Marie-Laure; Adrait, Annie; Khomich, Olga; Chapus, Fleur; Richaud, Mathieu; Hervieu, Maëva; Reiterer, Veronika; Centonze, Federica Grazia; Lucifora, Julie; Bartosch, Birke; Rivoire, Michel; Farhan, Hesso; Couté, Yohann; Mirakaj, Valbona; Decaens, Thomas; Mehlen, Patrick; Gibert, Benjamin; Zoulim, Fabien; Parent, Romain.

Hepatology; 76(5): 1345-1359, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-35253915

8.

Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.

Dominici, Chloé; Moreno-Bravo, Juan Antonio; Puiggros, Sergi Roig; Rappeneau, Quentin; Rama, Nicolas; Vieugue, Pauline; Bernet, Agnes; Mehlen, Patrick; Chédotal, Alain.

Nature; 545(7654): 350-354, 2017 05 18.

Artículo en Inglés | MEDLINE | ID: mdl-28445456

9.

Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1.

Moreno-Bravo, Juan Antonio; Roig Puiggros, Sergi; Blockus, Heike; Dominici, Chloé; Zelina, Pavol; Mehlen, Patrick; Chédotal, Alain.

Development; 145(2)2018 01 17.

Artículo en Inglés | MEDLINE | ID: mdl-29343638

10.

Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth.

Ménard, Marie; Costechareyre, Clélia; Ichim, Gabriel; Blachier, Jonathan; Neves, David; Jarrosson-Wuilleme, Loraine; Depping, Reinhard; Koster, Jan; Saintigny, Pierre; Mehlen, Patrick; Tauszig-Delamasure, Servane.

PLoS Biol; 16(5): e2002912, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29750782

11.

The dependence receptor TrkC triggers mitochondria-dependent apoptosis upon Cobra-1 recruitment.

Ichim, Gabriel; Genevois, Anne-Laure; Ménard, Marie; Yu, Li-Ying; Coelho-Aguiar, Juliana M; Llambi, Fabien; Jarrosson-Wuilleme, Loraine; Lefebvre, Jonathan; Tulasne, David; Dupin, Elisabeth; Le Douarin, Nicole; Arumäe, Urmas; Tauszig-Delamasure, Servane; Mehlen, Patrick.

Mol Cell; 51(5): 632-46, 2013 Sep 12.

Artículo en Inglés | MEDLINE | ID: mdl-24034695

12.

p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis.

Napoletano, Francesco; Gibert, Benjamin; Yacobi-Sharon, Keren; Vincent, Stéphane; Favrot, Clémentine; Mehlen, Patrick; Girard, Victor; Teil, Margaux; Chatelain, Gilles; Walter, Ludivine; Arama, Eli; Mollereau, Bertrand.

PLoS Genet; 13(9): e1007024, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-28945745

13.

The dependence receptor TrkC regulates the number of sensory neurons during DRG development.

Ménard, Marie; Costechareyre, Clélia; Coelho-Aguiar, Juliana M; Jarrosson-Wuilleme, Loraine; Rama, Nicolas; Blachier, Jonathan; Kindbeiter, Karine; Bozon, Muriel; Cabrera, Jorge R; Dupin, Elisabeth; Le Douarin, Nicole; Mehlen, Patrick; Tauszig-Delamasure, Servane.

Dev Biol; 442(2): 249-261, 2018 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-30071216

14.

Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.

Plissonnier, Marie-Laure; Lahlali, Thomas; Michelet, Maud; Lebossé, Fanny; Cottarel, Jessica; Beer, Melanie; Neveu, Grégory; Durantel, David; Bartosch, Birke; Accardi, Rosita; Clément, Sophie; Paradisi, Andrea; Devouassoux-Shisheboran, Mojgan; Einav, Shirit; Mehlen, Patrick; Zoulim, Fabien; Parent, Romain.

PLoS Biol; 14(3): e1002421, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-27031829

15.

Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes.

Barnault, Romain; Lahlali, Thomas; Plissonnier, Marie-Laure; Romero-López, Cristina; Laverdure, Noémie; Ducarouge, Benjamin; Rivoire, Michel; Mehlen, Patrick; Zoulim, Fabien; Parent, Romain.

Biochem Biophys Res Commun; 495(4): 2425-2431, 2018 01 22.

Artículo en Inglés | MEDLINE | ID: mdl-29277614

16.

The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.

Guenebeaud, Céline; Goldschneider, David; Castets, Marie; Guix, Catherine; Chazot, Guillaume; Delloye-Bourgeois, Céline; Eisenberg-Lerner, Avital; Shohat, Galit; Zhang, Mingjie; Laudet, Vincent; Kimchi, Adi; Bernet, Agnès; Mehlen, Patrick.

Mol Cell; 40(6): 863-76, 2010 Dec 22.

Artículo en Inglés | MEDLINE | ID: mdl-21172653

17.

Molecular characterization of Netrin-1 and APP receptor binding: New leads to block the progression of senile plaques in Alzheimer's disease.

Borel, Franck; Marzocca, Fanny; Delcros, Jean-Guy; Rama, Nicolas; Mehlen, Patrick; Ferrer, Jean-Luc.

Biochem Biophys Res Commun; 488(3): 466-470, 2017 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-28501620

18.

Netrin-4 regulates stiffness and metastasis.

Mehlen, Patrick; Fattet, Laurent.

Nat Mater; 20(6): 722-723, 2021 06.

Artículo en Inglés | MEDLINE | ID: mdl-34045700

19.

DCC constrains tumour progression via its dependence receptor activity.

Castets, Marie; Broutier, Laura; Molin, Yann; Brevet, Marie; Chazot, Guillaume; Gadot, Nicolas; Paquet, Armelle; Mazelin, Laetitia; Jarrosson-Wuilleme, Loraine; Scoazec, Jean-Yves; Bernet, Agnès; Mehlen, Patrick.

Nature; 482(7386): 534-7, 2011 Dec 11.

Artículo en Inglés | MEDLINE | ID: mdl-22158121

20.

Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells.

Devailly, Guillaume; Grandin, Mélodie; Perriaud, Laury; Mathot, Pauline; Delcros, Jean-Guy; Bidet, Yannick; Morel, Anne-Pierre; Bignon, Jean-Yves; Puisieux, Alain; Mehlen, Patrick; Dante, Robert.

Nucleic Acids Res; 43(12): 5838-54, 2015 Jul 13.

Artículo en Inglés | MEDLINE | ID: mdl-26007656

Portal de Búsqueda de la BVS España

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: